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A new article has been published introducing the HarPULL hardware and software platform, a new system for ultra-fast tracking of brain rhythms in real time.

One of the main challenges in the field of biofeedback and neuromodulation is the delay between recording brain activity and providing a stimulus. If brain states change faster than the system has time to react to them, the effectiveness of therapy is at risk. HarPULL solves this problem: it allows you to respond to brain activity with a delay of just 2 milliseconds, which is an order of magnitude faster than in most existing solutions.
The team at the Center for Bioelectric Interfaces tested the system in combination with transcranial magnetic stimulation (TMS), but the HarPULL architecture is universal — it can be adapted to other rapid neuromodulation methods. Due to its high speed and accuracy, the system opens up prospects for both precision therapy and fundamental research of rhythmic processes in the brain.

Article: Hardware-enabled low latency rhythmic brain state tracking for brain stimulation applications NeuroImage (2025)